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pentobarbital will lessen the level or influence of tamoxifen by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Watch.pentobarbital will reduce the level or effect of celecoxib by impacting hepatic enzyme CYP2C9/10 metabolism. Minimal/Importance Not known.buprenorphine subdermal implant and pentobarbital equally boost sedation. Preven